Description

Armodafinil is the R-enantiomer of modafinil, a central nervous system stimulant known for promoting wakefulness. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of finished pharmaceutical products. It is primarily required by pharmaceutical manufacturers and research institutions for the development and production of treatments for sleep disorders such as narcolepsy, obstructive sleep apnea, and shift work sleep disorder.

Application

• Pharmaceutical API: Primary active ingredient in prescription medications for excessive sleepiness.
• Narcolepsy Treatment: Formulated into tablets or capsules to manage symptoms of narcolepsy.
• Sleep Apnea Therapy: Used in adjunctive treatment for obstructive sleep apnea (OSA).
• Shift Work Disorder (SWD) Management: Key component in medications to improve wakefulness during work hours for individuals with SWD.
• Neurological Research: Serves as a reference standard and investigational compound in sleep-wake cycle and cognitive enhancement studies.
• Generic Drug Manufacturing: Sourced for the production of bioequivalent generic versions of branded armodafinil drugs.

Basic Information

Product Name	Armodafinil
CAS No.	112111-43-0
Molecular Formula	C15H15NO2S
Molecular Weight	273.35 g/mol
Synonyms	(R)-Modafinil; R-Modafinil; Armodafinil; Nuvigil (Brand Name); (2-[(R)-(Diphenylmethyl)sulfinyl]acetamide); (R)-2-[(Diphenylmethyl)sulfinyl]acetamide; CRL-40902; Benzhydrylsulfinylacetamide (R-enantiomer)
EINECS	Contact for details

Quality Control

Our Armodafinil is manufactured under strict quality management systems, targeting purity levels suitable for pharmaceutical applications. Quality is assured through comprehensive analytical testing, including HPLC for assay and related substances, chiral purity determination, and residual solvent analysis. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to ensure transparency and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Chiral Purity (Enantiomeric Excess)	≥ 99.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5%; Total impurities: ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.