Description

2-(4-Bromo-2-Fluorophenyl)-1,2-Dihydro-5-Methyl-3H-1,2,4-Triazol-3-One is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutics. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for its structural utility in creating molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Serves as a key scaffold for developing new-generation pesticides and herbicides, leveraging its heterocyclic triazolone core.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex molecules, especially those requiring a halogenated, fluorinated phenyl-triazolone moiety.
• Material Science Research: Investigated for potential applications in the development of specialty polymers and advanced functional materials.
• Bioconjugation & Probe Development: Utilized in research labs for creating biochemical probes and diagnostic agents due to its reactive sites.

Basic Information

Product Name	2-(4-Bromo-2-Fluorophenyl)-1,2-Dihydro-5-Methyl-3H-1,2,4-Triazol-3-One
CAS No.	111992-09-7
Molecular Formula	C9H7BrFN3O
Molecular Weight	272.08 g/mol
Synonyms	5-Methyl-2-(4-bromo-2-fluorophenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; 2-(4-Bromo-2-fluorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one; 1,2-Dihydro-5-methyl-3H-1,2,4-triazol-3-one, 2-(4-bromo-2-fluorophenyl)-; 4-Bromo-2-fluorophenyl triazolone derivative; CAS 111992-09-7
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-2-Fluorophenyl)-1,2-Dihydro-5-Methyl-3H-1,2,4-Triazol-3-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supported by a detailed Certificate of Analysis (COA). We adhere to relevant industry standards and can provide material suitable for research and development under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.