Description

2-(4-Fluoro-2-Methylphenyl)Oxirane is a high-purity, versatile epoxide building block characterized by its fluorinated aromatic structure. This compound is critical for introducing the reactive oxirane moiety into target molecules, enabling the synthesis of advanced intermediates with tailored properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a crucial building block for constructing novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & Polymer Chemistry: Used in the synthesis of fluorinated monomers and cross-linking agents for advanced polymers and liquid crystal displays (LCDs), improving thermal and chemical resistance.
• Material Science Research: Employed in surface modification and the development of specialty epoxy resins and coatings with specific adhesion and durability characteristics.
• Chemical Biology & Proteomics: Acts as an electrophilic probe for labeling nucleophilic residues in proteins, useful for activity-based protein profiling (ABPP) and inhibitor design.

Basic Information

Product Name	2-(4-Fluoro-2-Methylphenyl)Oxirane
CAS No.	111991-16-3
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	4-Fluoro-2-Methylstyrene Oxide; 1-(4-Fluoro-2-methylphenyl)oxirane; 2-Methyl-4-fluorostyrene oxide; (4-Fluoro-2-methylphenyl)ethylene oxide; 2-(4-Fluoro-2-methylphenyl)ethylene oxide; 4-Fluoro-α-methylstyrene oxide; 1,2-Epoxy-1-(4-fluoro-2-methylphenyl)ethane
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-2-Methylphenyl)Oxirane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.