Description

2-(3,4-Difluorophenyl)Oxirane is a high-value fluorinated epoxide building block, also known as 2-(3,4-Difluorophenyl)ethylene oxide. This compound is prized for its unique chemical reactivity, serving as a versatile intermediate for introducing a difluorophenyl-oxirane moiety into more complex molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the difluorophenyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials, including components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Employed to introduce fluorinated aromatic groups into polymer chains, potentially improving chemical resistance, thermal stability, and surface properties.
• Cross-coupling & Ring-Opening Reactions: Utilized in palladium-catalyzed cross-coupling and nucleophilic ring-opening reactions to create diverse chemical libraries for screening.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs) serving the life sciences sector.

Basic Information

Product Name	2-(3,4-Difluorophenyl)Oxirane
CAS No.	111991-13-0
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	2-(3,4-Difluorophenyl)ethylene oxide; 3,4-Difluorostyrene oxide; (3,4-Difluorophenyl)oxirane; 1,2-Epoxy-2-(3,4-difluorophenyl)ethane; Oxirane, 2-(3,4-difluorophenyl)-; 3',4'-Difluorostyrene oxide; 2-(3,4-Difluorophenyl)oxirane
EINECS	Contact for details

Quality Control

Our 2-(3,4-Difluorophenyl)Oxirane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards where required for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.