Description

2-Bromo-1-(5-Chloro-2-Methoxy-Phenyl)-Ethanone is a high-purity, light-sensitive bromoketone building block of significant interest in advanced organic synthesis. Its value lies in its precise molecular structure, which serves as a versatile electrophilic intermediate for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing benzofuran, indole, or other fused heterocyclic systems with potential biological activity.
• Agrochemical Synthesis: Used in research and development for creating new herbicides, fungicides, or insecticides, leveraging the reactivity of the bromo and ketone functional groups.
• Material Science Research: Serves as a building block for synthesizing organic ligands, photoactive compounds, or monomers for advanced polymers.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags due to its ability to undergo selective reactions with nucleophiles.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and cyclization methodologies.

Basic Information

Product Name	2-Bromo-1-(5-Chloro-2-Methoxy-Phenyl)-Ethanone
CAS No.	111841-05-5
Molecular Formula	C9H8BrClO2
Molecular Weight	263.52 g/mol
Synonyms	2-Bromo-1-(5-chloro-2-methoxyphenyl)ethan-1-one; 5'-Chloro-2'-methoxy-2-bromoacetophenone; 2-Bromo-5'-chloro-2'-methoxyacetophenone; 1-(5-Chloro-2-methoxyphenyl)-2-bromoethanone; α-Bromo-5-chloro-2-methoxyacetophenone; 2-Bromo-1-(5-chloro-2-methoxyphenyl)ethanone; (5-Chloro-2-methoxyphenyl) 2-bromoethanone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(5-Chloro-2-Methoxy-Phenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.