Description

Ethanone, 1-(5-Chloro-2-Methoxyphenyl)-2-Fluoro- (9Ci) is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring chloro, methoxy, and fluoro substituents, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical development teams engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a precursor in the design and production of advanced herbicides and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Used in the synthesis of specialty polymers and liquid crystals where the introduction of fluorine atoms can modify material properties like stability and mesophase behavior.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for developing novel electron-transport or host materials in OLED device fabrication.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological mechanisms and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	Ethanone, 1-(5-Chloro-2-Methoxyphenyl)-2-Fluoro- (9Ci)
CAS No.	111840-97-2
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	1-(5-Chloro-2-methoxyphenyl)-2-fluoroethanone; 2-Fluoro-1-(5-chloro-2-methoxyphenyl)ethanone; 5'-Chloro-2'-methoxy-2-fluoroacetophenone; 2-Fluoro-5'-chloro-2'-methoxyacetophenone; 1-Acetyl-5-chloro-2-methoxy-2-fluorobenzene; 2-Fluoro-1-(5-chloro-2-methoxyphenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(5-Chloro-2-Methoxyphenyl)-2-Fluoro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical parameters are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.