Description

1-((1R,3S,6R)-6-Methyl-7-Oxabicyclo[4.1.0]Heptan-3-Yl) Ethanone is a high-purity, chiral oxabicycloheptane derivative, serving as a critical advanced intermediate in organic synthesis. Its unique stereochemistry and functional group make it a valuable building block for constructing complex molecular architectures with precise spatial orientation. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, including potential antiviral, anti-inflammatory, or central nervous system (CNS) drugs.
• Asymmetric Catalysis: Used as a precursor or ligand in the synthesis of chiral catalysts for enantioselective synthesis, crucial for producing single-isomer compounds.
• Fragrance & Flavor Chemistry: Serves as a starting material for synthesizing complex, stereochemically defined odorants and flavor compounds.
• Agrochemical Research: Intermediate in the development of new, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Material Science: Building block for specialty polymers or liquid crystals where the rigid, oxygen-containing bicyclic structure imparts specific material properties.
• Academic & Process R&D: A valuable reference standard and reagent for methodological studies in synthetic organic chemistry and route scouting.

Basic Information

Product Name	1-((1R,3S,6R)-6-Methyl-7-Oxabicyclo[4.1.0]Heptan-3-Yl) Ethanone
CAS No.	111613-37-7
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	(1R,3S,6R)-3-Acetyl-6-methyl-7-oxabicyclo[4.1.0]heptane; 3-Acetyl-6-methyl-7-oxabicyclo[4.1.0]heptane, (1R,3S,6R)-; 1-[(1R,3S,6R)-6-Methyl-7-oxabicyclo[4.1.0]hept-3-yl]ethanone; Chiral Oxabicycloheptanone Derivative; 7-Oxabicyclo[4.1.0]heptane-3-acetic acid, 6-methyl-, methyl ester?; Contact for details on additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-((1R,3S,6R)-6-Methyl-7-Oxabicyclo[4.1.0]Heptan-3-Yl) Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (by HPLC/GC), chiral excess, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain purity and chiral integrity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC/GC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.