Description

1-Aziridinecarboxylic Acid, 2-(1,1-Dimethylethyl)-, Ethyl Ester is a specialized, high-purity aziridine derivative used as a key building block in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of pharmaceuticals, agrochemicals, and functional materials, enabling the introduction of the sterically hindered tert-butylaziridine moiety. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the fine chemical, pharmaceutical, and life science industries.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural motif can impart specific biological activity.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties such as adhesion, chemical resistance, or biocompatibility.
• Ligand and Catalyst Development: Employed in organometallic chemistry for constructing complex nitrogen-containing ligands used in asymmetric catalysis.
• Peptidomimetics and Bio-conjugation: Utilized in medicinal chemistry to create peptide analogs and for bio-conjugation techniques, linking molecules to biological entities.
• Academic and Industrial R&D: A valuable reagent for method development and exploring new chemical reactions in both university laboratories and corporate research centers.

Basic Information

Product Name	1-Aziridinecarboxylic Acid, 2-(1,1-Dimethylethyl)-, Ethyl Ester
CAS No.	111133-39-2
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Ethyl 2-(tert-butyl)aziridine-1-carboxylate; 2-tert-Butylaziridine-1-carboxylic acid ethyl ester; 1-(Ethoxycarbonyl)-2-tert-butylaziridine; Aziridine-1-carboxylic acid, 2-(1,1-dimethylethyl)-, ethyl ester; 2-tert-Butyl-1-ethoxycarbonylaziridine; N-Carbethoxy-2-tert-butylaziridine; tert-Butylaziridine-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1-Aziridinecarboxylic Acid, 2-(1,1-Dimethylethyl)-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to the reactive nature of the aziridine ring, it is recommended to store under an inert atmosphere for long-term stability and to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.