Description

1-Methyl-4-Trifluoroacetylthiosemicarbazide is a specialized organofluorine compound that serves as a versatile building block in advanced chemical synthesis. Its core value lies in the trifluoroacetyl and thiosemicarbazide functional groups, which are critical for introducing specific reactivity and fluorine-based properties into target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting infectious diseases or cancer, where the thiosemicarbazide moiety is pharmacologically significant.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the biological activity of the thiosemicarbazide structure.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocycles, such as triazoles and thiadiazoles, in academic and industrial R&D settings.
• Coordination Chemistry: Acts as a ligand for metal ions, useful in creating catalysts or materials with specific electronic properties.
• Fluorine Chemistry: Employed to introduce the trifluoromethyl group into organic molecules, a common strategy to modulate lipophilicity, metabolic stability, and bioavailability.

Basic Information

Product Name	1-Methyl-4-Trifluoroacetylthiosemicarbazide
CAS No.	110932-26-8
Molecular Formula	C5H7F3N3OS
Molecular Weight	214.19 g/mol
Synonyms	4-Methyl-1-(trifluoroacetyl)thiosemicarbazide; 1-Methyl-4-(trifluoroacetyl)thiosemicarbazide; N-Methyl-N'-(trifluoroacetyl)hydrazinecarbothioamide; 1-Methyl-1-(trifluoroacetyl)thiosemicarbazide; Trifluoroacetic acid (1-methylthiosemicarbazide); (Trifluoroacetyl)methylthiosemicarbazide
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-Trifluoroacetylthiosemicarbazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.