Description

(1R,3S)-2,2-Dimethyl-3-(2-Oxopropyl)-Cyclopropaneacetonitrile is a high-purity chiral cyclopropane derivative, a crucial advanced intermediate in modern organic synthesis. Its precise stereochemistry and functional groups make it an indispensable building block for creating complex, biologically active molecules with high enantiomeric purity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anti-inflammatory, or central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its cyclopropane structure contributes to the stability and efficacy of the final product.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex fragrance compounds, flavors, and other specialty fine chemicals requiring high stereochemical control.
• Material Science Precursor: Investigated as a monomer or building block for creating novel polymers with specific optical or structural properties.

Basic Information

Product Name	(1R,3S)-2,2-Dimethyl-3-(2-Oxopropyl)-Cyclopropaneacetonitrile
CAS No.	110847-02-4
Molecular Formula	C10H15NO
Molecular Weight	165.23 g/mol
Synonyms	(1R,3S)-2,2-Dimethyl-3-(2-oxopropyl)cyclopropaneacetonitrile; (1R-cis)-2,2-Dimethyl-3-(2-oxopropyl)cyclopropaneacetonitrile; 2,2-Dimethyl-3-(2-oxopropyl)cyclopropaneacetonitrile, (1R,3S)-; Chiral Cyclopropaneacetonitrile derivative; 3-(2-Oxopropyl)-2,2-dimethylcyclopropaneacetonitrile, (1R,3S)-; (1R,3S)-3-(2-Oxopropyl)-2,2-dimethylcyclopropaneacetonitrile
EINECS	Contact for details

Quality Control

Our (1R,3S)-2,2-Dimethyl-3-(2-Oxopropyl)-Cyclopropaneacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.