Description

3-Buten-2-One, 1-Chloro-3,4,4-Trifluoro- is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both a reactive α,β-unsaturated ketone moiety and a chlorotrifluoroethyl group, makes it a valuable precursor for introducing fluorinated segments into target molecules. This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel drug candidates, particularly for introducing fluorinated pharmacophores to improve metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and coatings with unique surface properties, such as oil and water repellency.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for cycloaddition reactions, nucleophilic additions, and other transformations to create complex, fluorinated organic structures.
• Liquid Crystal & Electronic Chemical: Investigated for use in the synthesis of fluorinated components for liquid crystal displays (LCDs) and other electronic materials.

Basic Information

Product Name	3-Buten-2-One, 1-Chloro-3,4,4-Trifluoro-
CAS No.	110784-75-3
Molecular Formula	C4H2ClF3O
Molecular Weight	158.51 g/mol
Synonyms	1-Chloro-3,4,4-trifluorobut-3-en-2-one; 3-Buten-2-one, 1-chloro-3,4,4-trifluoro-; 1-Chloro-3,4,4-trifluoro-3-buten-2-one; 3,4,4-Trifluoro-1-chlorobut-3-en-2-one; 4-Chloro-1,1,2-trifluorobut-3-en-2-one (tautomeric form); TFBK (abbreviation); Chlorotrifluorobuteneone
EINECS	Contact for details

Quality Control

Every batch of 1-Chloro-3,4,4-Trifluorobut-3-en-2-one is produced and analyzed under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles to ensure consistency and reliability for your critical synthesis workflows. Our standard R&D Grade material is characterized using advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and incompatible organic solvents. Due to its light-sensitive nature and reactive functional groups, prolonged exposure to heat, light, or moisture should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.