Description

1-Penten-3-One, 1,1,2-Trifluoro-4,4-Dimethyl- is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a reactive α,β-unsaturated ketone moiety and a trifluoromethyl group, makes it a valuable precursor for introducing fluorine atoms into complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It enables the synthesis of novel compounds with potentially enhanced biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of new active pharmaceutical ingredients (APIs), particularly those requiring fluorinated scaffolds to modulate bioavailability and potency.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the introduction of fluorine can improve environmental stability and efficacy.
• Material Science Precursor: Acts as a building block for fluorinated polymers, liquid crystals, or specialty coatings with unique surface properties and chemical resistance.
• Organic Synthesis Reagent: Employed in Michael addition reactions, cycloadditions, and other transformations to construct complex, fluorinated heterocycles and alicyclic compounds.
• Fluorine Chemistry Studies: Utilized in academic and industrial R&D to explore new methodologies for C-F bond formation and the behavior of fluorinated enones.

Basic Information

Product Name	1-Penten-3-One, 1,1,2-Trifluoro-4,4-Dimethyl-
CAS No.	110784-72-0
Molecular Formula	C7H9F3O
Molecular Weight	166.14 g/mol
Synonyms	4,4-Dimethyl-1,1,2-trifluoropent-1-en-3-one; 1,1,2-Trifluoro-4,4-dimethyl-1-penten-3-one; 4,4-Dimethyl-1,1,2-trifluoro-3-penten-1-one; 1-Penten-3-one, 1,1,2-trifluoro-4,4-dimethyl-; Trifluoromethylated enone building block
EINECS	Contact for details

Quality Control

Our 1-Penten-3-One, 1,1,2-Trifluoro-4,4-Dimethyl- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including GC, NMR, and IR spectroscopy, to confirm identity and purity. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to prevent degradation. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.