Description

2-(Benzyloxymethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a versatile organoboron reagent featuring a protected hydroxymethyl group. This compound is a critical building block in modern synthetic chemistry, enabling efficient carbon-carbon bond formation through Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of active pharmaceutical ingredients (APIs) and complex bioactive molecules via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific boronic ester functionalities.
• Material Science: Serves as a monomer or functionalization agent in the production of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Research & Development: A valuable reagent in academic and industrial labs for methodology development and library synthesis in medicinal chemistry.
• Liquid Crystal & Display Technology: Employed in the synthesis of advanced organic compounds for liquid crystal displays (LCDs).

Basic Information

Product Name	2-(Benzyloxymethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	110744-90-6
Molecular Formula	C₁₄H₂₁BO₃
Molecular Weight	248.13 g/mol
Synonyms	Benzyloxymethylboronic Acid Pinacol Ester; (Benzyloxymethyl)boronic Acid Pinacol Ester; 2-(Benzyloxymethyl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; Pinacol (Benzyloxymethyl)boronate; (Benzyloxymethyl)boronic Acid, Pinacol Ester; Benzyloxymethyl-Bpin; B-(Benzyloxymethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our production of 2-(Benzyloxymethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by NMR (1H, 13C, 11B), HPLC, and GC analysis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) for prolonged use or when dispensing from the original container to maintain optimal stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.