Description

Forskolin, 6Beta-[Beta'-(Piperidino)Propionyl]-, Hydrochloride is a chemically modified derivative of the natural forskolin diterpene, designed to enhance specific pharmacological properties. This compound is valued for its role as a potent and selective activator of adenylate cyclase, making it a critical research tool for studying cyclic AMP (cAMP)-mediated signaling pathways. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in metabolic, cardiovascular, and neurological research.

Application

• Biochemical Research: A key tool for investigating cAMP-dependent signal transduction mechanisms in cell-based assays.
• Pharmaceutical Development: Serves as a reference standard and a lead compound in drug discovery programs targeting metabolic disorders.
• Cardiovascular Studies: Used in research models to study vasodilation, cardiac contractility, and platelet aggregation.
• Metabolic Research: Applied in studies exploring lipolysis, insulin secretion, and thyroid hormone activation.
• Neuroscience: Employed to examine the role of cAMP in neurotransmitter release, synaptic plasticity, and neuroprotection.
• Reference Standard: Used for analytical method development, validation, and quality control in laboratory settings.

Basic Information

Product Name	Forskolin, 6Beta-[Beta'-(Piperidino)Propionyl]-, Hydrochloride
CAS No.	110452-77-2
Molecular Formula	C27H40N2O5 • HCl
Molecular Weight	509.08 g/mol
Synonyms	6β-[3'-(1-Piperidinyl)propionyl]forskolin hydrochloride; 6β-(3-Piperidinopropionyl)forskolin HCl; 1,9-Dideoxy-6β-[3-(1-piperidinyl)-1-oxopropyl]forskolin hydrochloride; 6β-(Piperidinopropionyl)forskolin hydrochloride; 6β-(3-Piperidinopropanoyl)forskolin hydrochloride; 6β-(Piperidinopropanoyl)forskolin HCl; 6β-(3-Piperidinopropionyl)-1,9-dideoxyforskolin hydrochloride
EINECS	Contact for details

Quality Control

Our Forskolin, 6Beta-[Beta'-(Piperidino)Propionyl]-, Hydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.