Description

1-Bromo-2-Chloro-4-Fluorobenzene is a high-purity halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its precise halogen substitution pattern makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a specific halogenated aromatic core.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms can enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Acts as a starting material for creating halogenated aromatic components used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating novel chemical entities in academic and industrial R&D labs.
• Dye & Pigment Intermediate: Used in the synthesis of specialized halogenated dyes and pigments for high-performance applications.

Basic Information

Product Name	1-Bromo-2-Chloro-4-Fluorobenzene
CAS No.	110407-59-5
Molecular Formula	C6H3BrClF
Molecular Weight	209.44 g/mol
Synonyms	2-Chloro-1-bromo-4-fluorobenzene; 4-Fluoro-2-chlorobromobenzene; 1-Bromo-2-chloro-4-fluoro-benzene; 2-Chloro-4-fluorobromobenzene; 4-Fluoro-2-chloro-1-bromobenzene; Benzene, 1-bromo-2-chloro-4-fluoro-; Bromochlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-4-Fluorobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.7 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.