Description

3-Piperidinecarboxylic Acid, 2-Methyl-, Ethyl Ester, (2R,3R)-Rel- is a high-purity, stereochemically defined piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, functionalized scaffold essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly those targeting the central nervous system.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, especially in neurological and psychiatric therapeutic areas.
• Agrochemical Synthesis: Building block for creating novel, stereospecific pesticides and herbicides with enhanced efficacy and selectivity.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for stereoselective chemical transformations.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for methodological studies in synthetic organic and medicinal chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	3-Piperidinecarboxylic Acid, 2-Methyl-, Ethyl Ester, (2R,3R)-Rel-
CAS No.	110287-64-4
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Ethyl (2R,3R)-2-methylnipecotate; rel-(2R,3R)-2-Methyl-3-piperidinecarboxylic acid ethyl ester; Ethyl 2-methyl-3-piperidinecarboxylate (rel-(2R,3R)-); 2-Methylnipecotic acid ethyl ester; (2R,3R)-2-Methylpiperidine-3-carboxylic acid ethyl ester (relative); 3-Piperidinecarboxylic acid, 2-methyl-, ethyl ester, (2R,3R)-rel-; Ethyl 2-methyl-3-piperidinecarboxylate
EINECS	Contact for details

Quality Control

Our production of 3-Piperidinecarboxylic Acid, 2-Methyl-, Ethyl Ester, (2R,3R)-Rel- adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques including chiral HPLC, GC, and NMR to verify identity, stereochemical purity, and impurity profiles. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (rel-(2R,3R)-)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.