Description

3-Isoxazolamine,4-Methyl-5-(Trifluoromethyl)-(9Ci) is a specialized heterocyclic building block containing a trifluoromethyl group, a key structural motif prized in modern chemical synthesis. This compound matters for its role as a versatile intermediate in the development of advanced pharmaceuticals and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity, metabolic stability, and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate the unique properties of the trifluoromethyl-isoxazole scaffold into novel molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced materials with tailored surface properties or optical characteristics.
• Chemical Biology Probe Development: Employed in medicinal chemistry to create molecular probes for studying enzyme mechanisms and protein-ligand interactions due to its distinctive heterocyclic structure.
• Fluorine Chemistry Research: A valuable substrate for exploring novel fluorination reactions and the synthesis of complex fluorinated heterocycles in academic and industrial R&D settings.

Basic Information

Product Name	3-Isoxazolamine,4-Methyl-5-(Trifluoromethyl)-(9Ci)
CAS No.	110234-47-4
Molecular Formula	C5H5F3N2O
Molecular Weight	166.10 g/mol
Synonyms	4-Methyl-5-(trifluoromethyl)-1,2-oxazol-3-amine; 4-Methyl-5-(trifluoromethyl)isoxazol-3-amine; 5-(Trifluoromethyl)-4-methyl-3-isoxazolamine; 3-Amino-4-methyl-5-(trifluoromethyl)isoxazole; 4-Methyl-5-trifluoromethyl-3-isoxazolamine; 3-Isoxazolamine, 4-methyl-5-(trifluoromethyl)-; 110234-47-4
EINECS	Contact for details

Quality Control

Our 3-Isoxazolamine,4-Methyl-5-(Trifluoromethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.