Description

Ethyl 3-Fluorobenzoylformate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications requiring precise fluorination.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated monomers for advanced polymers with unique optical or surface properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs of natural products for metabolic pathway studies and target identification.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	Ethyl 3-Fluorobenzoylformate
CAS No.	110193-59-4
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	Ethyl 3-fluorobenzoylformate; Ethyl 2-oxo-2-(3-fluorophenyl)acetate; 3-Fluorobenzoylformic Acid Ethyl Ester; 2-Oxo-2-(3-fluorophenyl)acetic Acid Ethyl Ester; Ethyl (3-fluorophenyl)(oxo)acetate; Ethyl α-oxo-3-fluorobenzeneacetate; Ethyl 3-fluoro-α-oxobenzeneacetate; Ethyl 3-fluorophenylglyoxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Fluorobenzoylformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.