Description

1,3-Dimethyl-5-[3-(Trifluoromethyl)Phenoxy]-1H-Pyrazole-4-Carbaldehyde is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. Its molecular architecture, featuring a pyrazole core, a trifluoromethylphenoxy group, and an aldehyde functionality, makes it a critical precursor for synthesizing complex bioactive molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a crucial building block for creating next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and environmental profile.
• Chemical Research & Development: Used in medicinal chemistry and process chemistry for lead optimization, structure-activity relationship (SAR) studies, and scaling up synthetic routes.
• Ligand and Catalyst Precursor: The aldehyde and heterocyclic nitrogen atoms can be utilized to construct sophisticated ligands for catalysis or metal-organic frameworks (MOFs).
• Material Science Applications: Potential use in the synthesis of specialty polymers or organic electronic materials due to its conjugated system and functional handles.

Basic Information

Product Name	1,3-Dimethyl-5-[3-(Trifluoromethyl)Phenoxy]-1H-Pyrazole-4-Carbaldehyde
CAS No.	109925-28-2
Molecular Formula	C13H11F3N2O2
Molecular Weight	284.24 g/mol
Synonyms	5-[3-(Trifluoromethyl)phenoxy]-1,3-dimethyl-1H-pyrazole-4-carbaldehyde; 1,3-Dimethyl-5-(3-trifluoromethylphenoxy)pyrazole-4-carboxaldehyde; 1H-Pyrazole-4-carboxaldehyde, 1,3-dimethyl-5-[3-(trifluoromethyl)phenoxy]-; 4-Formyl-1,3-dimethyl-5-(α,α,α-trifluoro-m-phenoxy)pyrazole
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-5-[3-(Trifluoromethyl)Phenoxy]-1H-Pyrazole-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot quality suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.