Description

2-Amino-4-(Trifluoromethyl)Benzaldehyde is a versatile aromatic aldehyde building block characterized by its amino and trifluoromethyl substituents. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, where the trifluoromethyl group enhances lipophilicity and metabolic stability. It is primarily needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and dyes due to its electron-withdrawing and donating functional groups.
• Fluorine Chemistry Studies: A valuable compound for research into the effects of fluorine substitution on aromatic reactivity and physical properties.

Basic Information

Product Name	2-Amino-4-(Trifluoromethyl)Benzaldehyde
CAS No.	109466-88-8
Molecular Formula	C8H6F3NO
Molecular Weight	189.14 g/mol
Synonyms	4-(Trifluoromethyl)-2-aminobenzaldehyde; 2-Amino-α,α,α-trifluoro-p-tolualdehyde; 2-Amino-4-trifluoromethylbenzaldehyde; 4-Trifluoromethylanthranilaldehyde; 2-Amino-4-(trifluoromethyl)benzaldehyde; 2-Amino-α,α,α-trifluoro-4-methylbenzaldehyde; 2-Amino-4-(trifluoromethyl)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.