Description

(3,4-Difluorophenyl)Acetaldehyde is a versatile aromatic aldehyde building block characterized by its difluorinated phenyl ring, which imparts unique electronic and steric properties. This compound is essential for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a difluorophenyl moiety into their target structures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates, especially in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluorophenyl group enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated organic electronic materials for displays and lighting.
• Functional Polymer Monomer: Incorporated into specialty polymers to modify thermal stability, chemical resistance, and optical properties.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for constructing complex aromatic aldehydes via further functionalization.
• Flavor & Fragrance Intermediate: Used in the synthesis of certain high-value aromatic compounds for specialty applications.

Basic Information

Product Name	(3,4-Difluorophenyl)Acetaldehyde
CAS No.	109346-84-1
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	2-(3,4-Difluorophenyl)acetaldehyde; 3,4-Difluorobenzeneacetaldehyde; (3,4-Difluorophenyl)ethanal; 2-(3,4-Difluorophenyl)ethanal; 3,4-Difluorophenylethanal; NSC 405124; 109346-84-1; α-(3,4-Difluorophenyl)acetaldehyde
EINECS	Contact for details

Quality Control

Our (3,4-Difluorophenyl)Acetaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress and oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.