Description

3-(2,5-Difluorophenyl)Prop-2-Yn-1-Ol (Wx191421) is a high-purity fluorinated alkyne derivative, serving as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a terminal alkyne and a difluorophenyl group, makes it an essential precursor for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides, leveraging the fluorine atoms for enhanced biological activity and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced materials with unique optical or electronic properties.
• Chemical Biology: Employed in click chemistry reactions (e.g., CuAAC) for bioconjugation and probe development due to its terminal alkyne functionality.
• Liquid Crystal & OLED Development: Acts as a core building block for fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale GMP batches for clinical trials.

Basic Information

Product Name	3-(2,5-Difluorophenyl)Prop-2-Yn-1-Ol (Wx191421)
CAS No.	109034-27-7
Molecular Formula	C9H6F2O
Molecular Weight	168.14 g/mol
Synonyms	2,5-Difluorophenyl propargyl alcohol; 1-(2,5-Difluorophenyl)-2-propyn-1-ol; 3-(2,5-Difluorophenyl)prop-2-yn-1-ol; 2-Propyn-1-ol, 1-(2,5-difluorophenyl)-; WX-191421; Wx191421
EINECS	Contact for details

Quality Control

Our 3-(2,5-Difluorophenyl)Prop-2-Yn-1-Ol (Wx191421) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, and we support our clients' regulatory needs for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.