Description

Ilexsaponin B1 CAS NO 109008-27-7 is a high-purity, bioactive triterpenoid saponin isolated from the *Ilex* genus, valued for its significant pharmacological potential. This compound is a critical reference standard and active ingredient for research and development in the pharmaceutical and nutraceutical sectors. It is primarily sought by manufacturers and research institutions focused on developing novel therapeutics for metabolic and inflammatory conditions.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and quantification of saponin content in herbal extracts and finished pharmaceutical products.
• Drug Discovery & Development: Serves as a key active pharmaceutical ingredient (API) intermediate in preclinical research for anti-inflammatory, anti-obesity, and hepatoprotective agents.
• Nutraceutical Formulation: Incorporated into high-end dietary supplements targeting metabolic syndrome, leveraging its bioactive properties.
• Biochemical Research: Utilized in in-vitro and in-vivo studies to investigate mechanisms of action related to lipid metabolism and insulin signaling pathways.
• Cosmeceutical Applications: Explored for use in skincare formulations for its potential anti-inflammatory and soothing properties.
• Analytical Chemistry: Acts as a critical calibration standard in advanced analytical techniques like HPLC and LC-MS for method development and validation.

Basic Information

Product Name	Ilexsaponin B1
CAS No.	109008-27-7
Molecular Formula	C48H76O19
Molecular Weight	957.1 g/mol
Synonyms	Ilexsaponin B1; Ilex saponin B1; 3-O-[β-D-Glucopyranosyl-(1→2)-β-D-glucopyranosyl-(1→2)-β-D-glucuronopyranosyl]-21β-hydroxy-22-oxoolean-12-en-28-oic acid β-D-glucopyranosyl ester; (3β,21β)-21-Hydroxy-3-[[O-β-D-glucopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranuronosyl]oxy]olean-12-en-28-oic acid β-D-glucopyranosyl ester
EINECS	Contact for details

Quality Control

Every batch of Ilexsaponin B1 is manufactured and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, MS, and NMR. Our quality commitment ensures the material is suitable for use as a pharmaceutical reference standard and in GLP-compliant research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Solvent Residues	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.