Description

3-[3-(4-Fluoro-Phenyl)-1-Phenyl-1H-Pyrazol-4-Yl]-Acrylic Acid CAS NO 108446-72-6 is a high-purity, functionalized pyrazole-acrylic acid derivative. This compound serves as a critical pharmaceutical intermediate and advanced organic building block for synthesizing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting inflammatory and neurological pathways.
• Agrochemical Research: Building block for developing new-generation herbicides and fungicides with enhanced efficacy.
• Material Science: Monomer or cross-linking agent in the development of specialty polymers and advanced organic frameworks (MOFs/COFs).
• Chemical Biology: Used as a probe or linker in bioconjugation and the development of chemical tools for biological study.
• Organic Synthesis: Versatile scaffold for constructing complex heterocyclic compounds in academic and industrial research.
• Fluorescent Dye Precursor: Intermediate in the synthesis of specialized fluorophores for imaging and sensing applications.

Basic Information

Product Name	3-[3-(4-Fluoro-Phenyl)-1-Phenyl-1H-Pyrazol-4-Yl]-Acrylic Acid
CAS No.	108446-72-6
Molecular Formula	C18H13FN2O2
Molecular Weight	308.31 g/mol
Synonyms	3-[3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]acrylic acid; (E)-3-[3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]acrylic acid; 4-(2-Carboxyvinyl)-3-(4-fluorophenyl)-1-phenylpyrazole; 3-(3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)prop-2-enoic acid; 108446-72-6; 4-Pyrazoleacrylic acid, 3-(4-fluorophenyl)-1-phenyl-; FPPA (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 3-[3-(4-Fluoro-Phenyl)-1-Phenyl-1H-Pyrazol-4-Yl]-Acrylic Acid is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.