Description

4-Nitropicolinaldehyde is a versatile and high-purity organic building block, specifically a nitrated heterocyclic aldehyde. This compound is valued for its dual functional groups, which make it a critical intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing pyridine and pyrimidine cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its reactive aldehyde and nitro groups.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological systems.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions to form complex biaryl structures.

Basic Information

Product Name	4-Nitropicolinaldehyde
CAS No.	108338-19-8
Molecular Formula	C6H4N2O3
Molecular Weight	152.11 g/mol
Synonyms	4-Nitro-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 4-nitro-; Picolinaldehyde, 4-nitro-; 4-Nitro-2-formylpyridine; 4-Nitropyridine-2-carbaldehyde; 2-Formyl-4-nitropyridine; 4-Nitro-2-pyridylaldehyde; 4-Nitropicolinaldehyde
EINECS	Contact for details

Quality Control

Our 4-Nitropicolinaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We adhere to cGMP principles for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.