Description

16-o-Methyl-Cafestol is a specific methylated derivative of cafestol, a key diterpene compound found in coffee beans. This compound is of significant interest in biochemical and pharmacological research due to its role as a specific biomarker and its potential biological activities. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical development companies engaged in the study of coffee constituents, metabolic pathways, and bioactive natural products.

Application

• Biochemical Research: Used as a high-purity reference standard for studying the metabolism and biological effects of coffee diterpenes.
• Analytical Standard: Serves as a critical calibration standard in HPLC, LC-MS, and GC-MS methods for the quantification of cafestol and its derivatives in coffee, food products, and biological samples.
• Phytochemical Studies: Employed in the isolation, identification, and characterization of coffee bean components and their synthetic analogs.
• Pharmacological Investigation: A tool compound for in vitro and in vivo studies to explore potential bioactivities, such as effects on cholesterol metabolism or enzyme modulation.
• Food & Beverage Analysis: Essential for quality control and authenticity testing within the coffee industry to profile specific diterpene markers.
• Method Development & Validation: Used by analytical chemists to develop and validate robust testing protocols for complex natural product matrices.

Basic Information

Product Name	16-o-Methyl-Cafestol
CAS No.	108214-28-4
Molecular Formula	C21H28O3
Molecular Weight	328.45 g/mol
Synonyms	16-O-Methylcafestol; 16-Methoxycafestol; Cafestol 16-methyl ether; (13R)-16-Methoxy-13-methyl-17-(6-methylhept-5-en-2-yl)-4,5,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-ol; 16-Methoxy-13-methyl-17-(6-methylhept-5-en-2-yl)-4,5,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-ol
EINECS	Contact for details

Quality Control

Our 16-o-Methyl-Cafestol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chromatographic data is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. Keep the container sealed to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.