Description

Sorangicin B is a potent secondary metabolite belonging to the polyketide class of antibiotics, isolated from the myxobacterium *Sorangium cellulosum*. This compound is of significant interest in research and development due to its unique mechanism of action, which involves the inhibition of bacterial RNA polymerase. It is primarily sought after by pharmaceutical research institutions, biotechnology companies, and academic laboratories engaged in the discovery of novel antimicrobial agents and the study of bacterial transcription mechanisms.

Application

• Antibiotic Research & Development: As a lead compound for the development of new classes of antibiotics targeting drug-resistant bacterial pathogens.
• Mechanistic Studies: Used as a specific biochemical tool to investigate the function and inhibition of bacterial RNA polymerase in molecular biology.
• Microbiology & Pharmacology: Employed in *in vitro* and *in vivo* studies to evaluate antimicrobial activity spectra and efficacy.
• Chemical Biology: Serves as a molecular probe for studying bacterial cell processes and for structure-activity relationship (SAR) analysis.
• Biopharmaceutical Production: Potential use in fermentation process studies and the biosynthesis of complex natural products.

Basic Information

Product Name	Sorangicin B
CAS No.	107745-54-0
Molecular Formula	C46H66N2O13
Molecular Weight	878.99 g/mol
Synonyms	Sorangicin B; Antibiotic Sorangicin B; Soraphen B; Soraphen A analog; 2-Butenoic acid, 2-methyl-, (2E,4E,6E,8E,10E,12E,14E,16E,18E)-20-[(3S,4R,5S,6S)-4,5-dihydroxy-6-methyl-3-(methylamino)tetrahydro-2H-pyran-2-yl]-5,9,13,17-tetramethyl-20-oxo-3,6-epoxy-1-oxacycloeicosa-2,4,6,8,10,12,14,16,18-nonaen-11-yl ester; (2E,4E,6E,8E,10E,12E,14E,16E,18E)-20-[(3S,4R,5S,6S)-4,5-Dihydroxy-6-methyl-3-(methylamino)oxan-2-yl]-5,9,13,17-tetramethyl-20-oxo-3,6-epoxy-1-oxacycloeicosa-2,4,6,8,10,12,14,16,18-nonaen-11-yl 2-methylbut-2-enoate
EINECS	Contact for details

Quality Control

Our Sorangicin B is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including purity determination and identity confirmation. Certificates of Analysis (COA) detailing specific test results are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the product to equilibrate to room temperature in a dry environment before opening to minimize moisture condensation. Store in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 1.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.