Description

Ginkgolide J is a highly specific and potent platelet-activating factor (PAF) receptor antagonist isolated from the Ginkgo biloba tree. This compound is of significant interest in advanced pharmaceutical research and development due to its targeted biological activity. It is primarily utilized by researchers and manufacturers in the nutraceutical, pharmaceutical, and reference standard sectors for developing novel therapeutic agents and high-purity analytical standards.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and assay validation of Ginkgo biloba extracts and finished products.
• Bioactive Ingredient R&D: Serves as a key intermediate or active pharmaceutical ingredient (API) in research focused on cardiovascular, cerebrovascular, and inflammatory disorders.
• Nutraceutical Formulation: Incorporated into high-end dietary supplements targeting cognitive support and circulatory health, where standardized, high-purity actives are required.
• Mechanistic Studies: Employed in pharmacological and biochemical research to study PAF-mediated pathways and screen for new receptor antagonists.
• Analytical Chemistry: Essential for developing and calibrating analytical methods such as HPLC and LC-MS for the precise quantification of ginkgolides in complex matrices.

Basic Information

Product Name	Ginkgolide J
CAS No.	107438-79-9
Molecular Formula	C20H24O10
Molecular Weight	424.40 g/mol
Synonyms	Ginkgolide-J; (1R,2S,3R,6S,10S,14S)-5,10-Dihydroxy-3,14,20,20-tetramethyl-1-(3-methylbut-2-en-1-yl)-4,8,15,19-tetraoxahexacyclo[11.7.0.0²,¹⁰.0³,⁶.0¹⁴,¹⁸.0¹⁵,¹⁹]icosane-9,16-dione; Bilobalide related compound J; PAF antagonist from Ginkgo biloba
EINECS	Contact for details

Quality Control

Our Ginkgolide J is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.