Description

2-Methoxycarbonylaminopyridine-5-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and boronic acids, fundamental in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing pyridine scaffolds.
• Agrochemical Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Ligand and Catalyst Preparation: Acts as a precursor for creating specialized ligands used in catalysis and material science.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and bioconjugates for target identification and validation.
• Advanced Material Synthesis: Facilitates the creation of organic electronic materials, such as those used in OLEDs and semiconductors.

Basic Information

Product Name	2-Methoxycarbonylaminopyridine-5-Boronic Acid, Pinacol Ester
CAS No.	107337-20-2
Molecular Formula	C14H19BN2O4
Molecular Weight	290.13 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(methoxycarbonylamino)pyridine; 2-(Methoxycarbonylamino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(Methoxycarbonylamino)pyridine-5-boronic acid pinacol ester; 2-Carbomethoxamido-5-pyridineboronic acid pinacol ester; 2-(Methoxycarbonylamino)-5-pyridineboronic acid pinacol ester; 5-Borono-2-(methoxycarbonylamino)pyridine pinacol ester; N-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl) carbamic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Methoxycarbonylaminopyridine-5-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.