Description

3-Aminopyridine-5-Boronic Acid, Pinacol Ester is a high-value boronic ester derivative, a key protected intermediate in modern synthetic chemistry. Its primary value lies in its stability and reactivity, making it a crucial building block for constructing complex molecules via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides that require specific pyridine-based structures.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and sensors for studying biological processes.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for clients.

Basic Information

Product Name	3-Aminopyridine-5-Boronic Acid, Pinacol Ester
CAS No.	107335-49-9
Molecular Formula	C11H17BN2O2
Molecular Weight	220.08 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-amine; 3-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Amino-5-pyridineboronic acid pinacol ester; 3-Amino-5-(pinacolboryl)pyridine; 5-Aminopyridine-3-boronic acid pinacol ester; 3-Pyridinamine, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; B-(3-Amino-5-pyridinyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Aminopyridine-5-Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production use. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.