Description

Methyl (2E)-2-Cyano-3-(3,4,5-Trimethoxyphenyl)Acrylate is a high-purity, versatile chemical intermediate featuring a conjugated cyanoacrylate structure with a trimethoxyphenyl substituent. This compound is valued for its role as a key building block in the synthesis of complex organic molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting kinase inhibition or possessing complex heterocyclic structures.
• Agrochemical Synthesis: Used in the development of novel active ingredients for crop protection, leveraging its electron-deficient acrylate moiety for further functionalization.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for constructing electron-transport or emissive layer materials due to its conjugated π-system.
• Dye and Pigment Manufacturing: Acts as a key intermediate for synthesizing advanced colorants and functional dyes with specific optical properties.
• Academic and Industrial R&D: Employed in methodological studies and the discovery of new chemical reactions, such as cycloadditions or cross-coupling processes.
• Liquid Crystal and Advanced Material Research: The rigid, planar core of the molecule makes it a candidate for developing components of liquid crystal displays or other ordered materials.

Basic Information

Product Name	Methyl (2E)-2-Cyano-3-(3,4,5-Trimethoxyphenyl)Acrylate
CAS No.	107115-22-0
Molecular Formula	C14H15NO5
Molecular Weight	277.27 g/mol
Synonyms	Methyl 2-Cyano-3-(3,4,5-trimethoxyphenyl)acrylate; (2E)-2-Cyano-3-(3,4,5-trimethoxyphenyl)-2-propenoic acid methyl ester; Methyl (E)-2-cyano-3-(3,4,5-trimethoxyphenyl)acrylate; 3,4,5-Trimethoxybenzylidenecyanoacetic acid methyl ester; 2-Propenoic acid, 2-cyano-3-(3,4,5-trimethoxyphenyl)-, methyl ester, (2E)-; Methyl α-cyano-3,4,5-trimethoxycinnamate; CN-TMPA Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl (2E)-2-Cyano-3-(3,4,5-Trimethoxyphenyl)Acrylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) detailing all critical parameters are provided with every shipment. We support development and commercial projects requiring material that meets stringent ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.