Description

3'-Fluoro-4'-Methylpropiophenone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a key strategy for modulating biological activity and metabolic stability. It is essential for research chemists and process development scientists engaged in creating novel active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including potential CNS agents and anti-inflammatory compounds.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the fluorine atom to enhance efficacy and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal molecules used in display technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, Grignard reactions, and reductions to create more complex fluorinated aromatic structures.
• Chemical Research & Development: Utilized in academic and industrial R&D for method development and exploring new fluorination pathways.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	3'-Fluoro-4'-Methylpropiophenone
CAS No.	107076-07-3
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	1-(3-Fluoro-4-methylphenyl)propan-1-one; 3-Fluoro-4-methylpropiophenone; Propiophenone, 3'-fluoro-4'-methyl-; 1-Propanone, 1-(3-fluoro-4-methylphenyl)-; 3-Fluoro-4-methyl-1-phenyl-1-propanone; 3-Fluoro-4-methylpropiophenone; 3'-Fluoro-4'-methylpropiophenone; 3-Fluoro-4-methyl phenyl ethyl ketone
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-4'-Methylpropiophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC/GC purity, identity confirmation by IR and NMR, and control of key impurities. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment supports applications requiring material of consistent high grade for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.