Description

4'-Bromo-2-(4-Fluorophenyl)Acetophenone is a high-purity organic building block characterized by its distinct bromo and fluoro substituents, which are critical for directing subsequent chemical transformations. This compound matters as a versatile and valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and advanced material scientists for applications in medicinal chemistry, ligand synthesis, and the development of functional organic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluorophenyl moiety.
• Material Science Research: Serves as a building block for creating organic ligands, liquid crystals, and advanced polymers with specific electronic or optical properties.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the development of molecular libraries for high-throughput screening.
• Chemical Research: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive bromo group, enabling the construction of complex biaryl systems.

Basic Information

Product Name	4'-Bromo-2-(4-Fluorophenyl)Acetophenone
CAS No.	107028-32-0
Molecular Formula	C14H10BrFO
Molecular Weight	293.13 g/mol
Synonyms	2-(4-Bromophenyl)-1-(4-fluorophenyl)ethanone; 1-(4-Bromophenyl)-2-(4-fluorophenyl)ethanone; 4'-Bromo-4-fluorobenzyl Phenyl Ketone; 4-Bromo-α-(4-fluorophenyl)acetophenone; p-Bromo-p'-fluoro deoxybenzoin; (4-Bromophenyl)(4-fluorophenyl)methanone (common misnomer); 107028-32-0; 4'-Bromo-2-(4-fluorophenyl)acetophenone
EINECS	Contact for details

Quality Control

Our 4'-Bromo-2-(4-Fluorophenyl)Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.