Description

1-Cyclohexyl-2,2,2-trifluoroethan-1-ol is a chiral fluorinated alcohol building block of significant interest in advanced organic synthesis. Its unique structure, featuring a trifluoroethyl alcohol moiety attached to a cyclohexyl ring, makes it a valuable intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs that can enhance bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorinated segment can improve environmental stability and efficacy.
• Liquid Crystal Materials: Acts as a component in the synthesis of fluorinated liquid crystals for display technologies, leveraging its specific polarity and steric profile.
• Advanced Polymer Chemistry: Employed as a monomer or modifier to create specialty polymers with tailored surface properties, chemical resistance, or optical characteristics.
• Catalyst Ligand Precursor: Useful in the preparation of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Organic Electronic Materials: Investigated as a building block for materials used in organic light-emitting diodes (OLEDs) and semiconductors.

Basic Information

Item	Details
Product Name	1-Cyclohexyl-2,2,2-trifluoroethan-1-ol
CAS No.	107018-38-2
Molecular Formula	C8H13F3O
Molecular Weight	182.18 g/mol
Synonyms	α-(Trifluoromethyl)cyclohexanemethanol; (1-Cyclohexyl-2,2,2-trifluoroethoxy)cyclohexane; 2,2,2-Trifluoro-1-cyclohexylethanol; 1-Cyclohexyl-2,2,2-trifluoroethanol; Cyclohexyl(trifluoromethyl)methanol; (Cyclohexyl)(trifluoromethyl)methanol; 107018-38-2
EINECS	Contact for details

Quality Control

Our 1-Cyclohexyl-2,2,2-trifluoroethan-1-ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.