Description

2-(3-Bromo-2-Methylphenyl)-1,3-Dioxolane is a specialized brominated aromatic acetal building block of significant interest in advanced organic synthesis. This compound matters for its role as a key protected aldehyde intermediate, offering chemists a stable and reactive handle for constructing complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, as well as by fine chemical manufacturers engaged in custom synthesis and process development.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted benzaldehyde motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the bromo-methylphenyl moiety is required.
• Ligand and Catalyst Development: Acts as a starting material for creating sophisticated chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its aromatic and halogenated structure.
• Custom & Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Facilitates methodological studies and the exploration of new chemical reactions in university and corporate research laboratories.

Basic Information

Product Name	2-(3-Bromo-2-Methylphenyl)-1,3-Dioxolane
CAS No.	106965-50-8
Molecular Formula	C11H13BrO2
Molecular Weight	257.12 g/mol
Synonyms	1,3-Dioxolane, 2-(3-bromo-2-methylphenyl)-; 3-Bromo-2-methylbenzaldehyde ethylene acetal; 2-(3-Bromo-o-tolyl)-1,3-dioxolane; (3-Bromo-2-methylphenyl)ethylene acetal; 3'-Bromo-2'-methylacetophenone ethylene ketal (common misnomer); 3-Bromo-2-methylbenzaldehyde acetal; Bromo-methylphenyl dioxolane
EINECS	Contact for details

Quality Control

Our 2-(3-Bromo-2-Methylphenyl)-1,3-Dioxolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports compliance with cGMP and ISO standards where required for your development and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.