Description

4-Benzyl-5-Oxo-Morpholine-3-Carboxylic Acid Methyl Ester is a high-purity, synthetically valuable heterocyclic building block. This compound is a key chiral intermediate in the synthesis of complex pharmaceutical molecules, offering a versatile scaffold for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Organic Synthesis Building Block: Used in the construction of complex morpholine and piperazine derivatives for medicinal chemistry and material science applications.
• Asymmetric Catalyst Research: Serves as a precursor or ligand in the development of new asymmetric catalytic systems.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of high-value fine chemicals.
• Academic & Industrial R&D: A valuable reagent for chemical libraries and structure-activity relationship (SAR) studies in both academic and corporate research laboratories.

Basic Information

Product Name	4-Benzyl-5-Oxo-Morpholine-3-Carboxylic Acid Methyl Ester
CAS No.	106910-81-0
Molecular Formula	C14H15NO4
Molecular Weight	261.27 g/mol
Synonyms	Methyl 4-benzyl-5-oxomorpholine-3-carboxylate; 3-Carbomethoxy-4-benzyl-5-morpholone; 5-Oxo-4-benzylmorpholine-3-carboxylic acid methyl ester; 4-Benzyl-5-oxo-3-morpholinecarboxylic acid methyl ester; 106910-81-0; Methyl 4-benzyl-5-oxo-3,4-dihydro-2H-1,4-oxazine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Benzyl-5-Oxo-Morpholine-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.