Description

2,2,2-Trifluoroethyl 2-Hydroxy-5-(2,2,2-Trifluoroethoxy)Benzoate is a high-value fluorinated organic intermediate characterized by its unique benzoate ester structure containing trifluoroethoxy and trifluoroethyl groups. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the introduction of fluorine atoms is essential for modulating properties like metabolic stability, lipophilicity, and bioavailability. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in areas requiring fluorinated motifs for improved pharmacokinetics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where fluorine incorporation enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, improving their chemical resistance and surface properties.
• Organic Electronics: A potential building block for electron-transport materials or semiconductors in OLEDs and organic photovoltaics.
• Complex Ligand Synthesis: Useful in preparing specialized ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	2,2,2-Trifluoroethyl 2-Hydroxy-5-(2,2,2-Trifluoroethoxy)Benzoate
CAS No.	106854-80-2
Molecular Formula	C11H8F6O4
Molecular Weight	318.17 g/mol
Synonyms	5-(2,2,2-Trifluoroethoxy)-2-hydroxybenzoic Acid 2,2,2-Trifluoroethyl Ester; 2,2,2-Trifluoroethyl 5-(2,2,2-Trifluoroethoxy)salicylate; Benzoic acid, 2-hydroxy-5-(2,2,2-trifluoroethoxy)-, 2,2,2-trifluoroethyl ester; Trifluoroethyl Trifluoroethoxysalicylate; 106854-80-2; TFETFES
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoroethyl 2-Hydroxy-5-(2,2,2-Trifluoroethoxy)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.