Description

Boronic Acid, (2-Propyl-5-Pyrimidinyl)-, Dimethyl Ester (9Ci) is a specialized organoboron compound with the CAS registry number 106832-86-4. This chemical serves as a crucial synthetic intermediate, valued for its role in cross-coupling reactions like the Suzuki-Miyaura reaction, which is fundamental to modern pharmaceutical and advanced materials research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require pyrimidine-based structures.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
• Suzuki-Miyaura Cross-Coupling: Acts as a pivotal boron reagent for forming carbon-carbon bonds between aromatic rings, a cornerstone reaction in medicinal and process chemistry.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Item	Detail
Product Name	Boronic Acid, (2-Propyl-5-Pyrimidinyl)-, Dimethyl Ester (9Ci)
CAS No.	106832-86-4
Molecular Formula	C9H14BNO2
Molecular Weight	179.03 g/mol
Synonyms	(2-Propylpyrimidin-5-yl)boronic acid dimethyl ester; Dimethyl (2-propylpyrimidin-5-yl)boronate; 5-(Dimethoxyboryl)-2-propylpyrimidine; 2-Propyl-5-pyrimidineboronic acid dimethyl ester; 106832-86-4; (2-Propyl-5-pyrimidinyl)boronic acid dimethyl ester
EINECS	Contact for details

Quality Control

Every batch of Boronic Acid, (2-Propyl-5-Pyrimidinyl)-, Dimethyl Ester is produced and tested under a strict quality management system. We ensure high purity and consistency suitable for research and development applications. Comprehensive analytical testing, including HPLC, NMR, and GC, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) documenting all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.