Description

1,3-Dioxolane-4-Carboxaldehyde, 2,2,4,5-Tetramethyl-, (4R-Trans)- (9Ci) is a high-purity, chiral dioxolane derivative serving as a critical synthetic intermediate. Its value lies in its stereochemically defined structure, which is essential for imparting specific biological activity or material properties in advanced syntheses. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the construction of complex, optically active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral active pharmaceutical ingredients (APIs), particularly in antiviral, antifungal, or neurological drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel, stereoselective pesticides and herbicides where specific chirality enhances efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Flavor and Fragrance Chemistry: Potential intermediate for producing specific, high-value chiral aroma chemicals.
• Material Science Research: Investigated as a monomer or modifying agent for polymers requiring specific stereoregularity.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and stereochemistry.

Basic Information

Item	Details
Product Name	1,3-Dioxolane-4-Carboxaldehyde, 2,2,4,5-Tetramethyl-, (4R-Trans)- (9Ci)
CAS No.	106622-89-3
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	(4R-trans)-2,2,4,5-Tetramethyl-1,3-dioxolane-4-carboxaldehyde; (4R,5S)-2,2,4,5-Tetramethyl-1,3-dioxolane-4-carbaldehyde; (4R,5S)-4-Formyl-2,2,4,5-tetramethyl-1,3-dioxolane; trans-2,2,4,5-Tetramethyl-1,3-dioxolane-4-carboxaldehyde; (4R,5S)-Tetramethyl-1,3-dioxolane-4-carboxaldehyde; 4R-2,2,4,5-Tetramethyl-1,3-dioxolane-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxaldehyde, 2,2,4,5-Tetramethyl-, (4R-Trans)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure high chemical and stereochemical purity suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.