Description

1,3-Dioxolane-4-Carboxaldehyde, 2,2,4,5-Tetramethyl-, (4S-Cis)- (9Ci) is a high-value, stereochemically defined chiral building block and aldehyde derivative. This compound is essential for its role in asymmetric synthesis, serving as a key precursor for complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of advanced, stereospecific pesticides and herbicides.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in catalytic processes.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.
• Material Science: Potential precursor for the development of novel polymers or functional materials with specific chiral properties.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxaldehyde, 2,2,4,5-Tetramethyl-, (4S-Cis)- (9Ci)
CAS No.	106622-88-2
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	(4S-cis)-2,2,4,5-Tetramethyl-1,3-dioxolane-4-carboxaldehyde; (4S,5S)-2,2,4,5-Tetramethyl-1,3-dioxolane-4-carbaldehyde; (4S,5S)-2,2,4,5-Tetramethyl-1,3-dioxolane-4-carboxaldehyde; (4S,5S)-4-Formyl-2,2,4,5-tetramethyl-1,3-dioxolane; 4S-cis-2,2,4,5-Tetramethyl-1,3-dioxolane-4-carboxaldehyde; (4S,5S)-Tetramethyl-1,3-dioxolane-4-carboxaldehyde; Chiral Dioxolane Aldehyde
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxaldehyde, 2,2,4,5-Tetramethyl-, (4S-Cis)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.