Description

6,8-Dibromo-3-(2-Bromoacetyl)Coumarin is a highly functionalized brominated coumarin derivative, serving as a versatile and reactive synthetic intermediate. Its multi-brominated structure makes it a critical precursor for the synthesis of complex heterocyclic compounds and advanced pharmaceutical scaffolds. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting enzyme inhibition or possessing fluorescent properties for bio-imaging.
• Agrochemical Research: Used in the development of new active ingredients for crop protection agents, leveraging its reactive halogen sites for further derivatization.
• Organic Synthesis: A versatile electrophile in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to create complex coumarin-based libraries.
• Fluorescent Probe Development: Serves as a core structure for designing and synthesizing novel fluorescent dyes and sensors due to the inherent photophysical properties of the coumarin scaffold.
• Material Science Precursor: Used in the research of organic electronic materials, such as OLEDs or nonlinear optical (NLO) materials, where bromine atoms facilitate further polymerization or functionalization.
• Academic & R&D: Essential for fundamental research in medicinal chemistry, photochemistry, and synthetic methodology development at universities and corporate R&D centers.

Basic Information

Product Name	6,8-Dibromo-3-(2-Bromoacetyl)Coumarin
CAS No.	106578-20-5
Molecular Formula	C₁₁H₅Br₃O₃
Molecular Weight	440.87 g/mol
Synonyms	3-(2-Bromoacetyl)-6,8-dibromocoumarin; 6,8-Dibromo-3-(bromoacetyl)-2H-chromen-2-one; 2-Bromo-1-(6,8-dibromo-2-oxo-2H-chromen-3-yl)ethan-1-one; 6,8-Dibromo-3-(bromoacetyl)coumarin; Dibromobromoacetylcoumarin
EINECS	Contact for details

Quality Control

Every batch of 6,8-Dibromo-3-(2-Bromoacetyl)Coumarin is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your research and development processes. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. A Certificate of Analysis (COA) detailing all specifications is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.