Description

Cholesteryl Diazoacetate is a specialized diazo-functionalized cholesterol derivative that serves as a versatile intermediate in advanced organic synthesis. Its unique structure, featuring a reactive diazoacetate group attached to the sterol backbone, makes it a valuable precursor for the synthesis of complex molecules and functional materials. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for applications ranging from novel drug discovery to the development of photoresponsive polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroidal drugs and bioactive compounds, particularly in cancer research and hormone therapy development.
• Advanced Material Synthesis: Precursor for creating photoresponsive polymers, liquid crystals, and functionalized surfaces via carbene insertion or cyclopropanation reactions.
• Agrochemical Research: Used in the development of new plant growth regulators and targeted pesticides with sterol-based activity.
• Chemical Biology Probes: Enables the site-specific labeling and cross-linking of biomolecules for studying protein-lipid interactions and membrane dynamics.
• Polymer Modification: Facilitates the grafting of cholesterol moieties onto polymer chains to alter material properties like biocompatibility and self-assembly behavior.
• Academic & Industrial R&D: Serves as a critical reagent in methodological development for new C-H functionalization and cycloaddition reactions.

Basic Information

Product Name	Cholesteryl Diazoacetate
CAS No.	106471-96-9
Molecular Formula	C29H46N2O2
Molecular Weight	454.70 g/mol
Synonyms	Cholesteryl 2-diazoacetate; Diazoacetic Acid Cholesteryl Ester; 3β-Cholest-5-en-3-yl 2-diazoacetate; NSC 334368; (3β)-Cholest-5-en-3-yl 2-diazoacetate; Cholesterol Diazoacetate; Cholesteryl Diazoethanoate
EINECS	Contact for details

Quality Control

Our Cholesteryl Diazoacetate is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and the reactivity of the diazo group, prolonged exposure to light, heat, or moisture should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.