Description

tert-Butyl [(1R)-1-Formyl-2-Methylpropyl]Carbamate is a high-value chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound matters because it provides a versatile handle for constructing complex, stereochemically defined molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of peptide-based drugs and other bioactive molecules.
• Peptidomimetic Research: Used to introduce protected amino acid motifs into novel compounds designed to mimic peptide function.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to create enantiomerically pure products.
• API Development: Employed in the research, development, and scale-up of new Active Pharmaceutical Ingredients (APIs), especially those requiring specific stereochemistry.
• Chemical Biology Probes: Useful for the synthesis of labeled or modified amino acid derivatives used in biochemical and cellular studies.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Item	Details
Product Name	tert-Butyl [(1R)-1-Formyl-2-Methylpropyl]Carbamate
CAS No.	106391-88-2
Molecular Formula	C10H19NO3
Molecular Weight	201.26 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-3-methylbutanal; Boc-L-valinal; N-Boc-L-valinal; N-(tert-Butoxycarbonyl)-L-valinal; (R)-N-Boc-2-amino-3-methylbutyraldehyde; tert-Butyl N-[(1R)-1-formyl-2-methylpropyl]carbamate; Boc-Valinal; L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-, aldehyde
EINECS	Contact for details

Quality Control

Our tert-Butyl [(1R)-1-Formyl-2-Methylpropyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Allow the container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.