Description

Ethyl 3-Chloro-2,2-Dimethylpropanoate is a versatile chlorinated ester building block with a sterically hindered structure, offering unique reactivity for advanced synthesis. This compound is valued for its role as a key intermediate in the production of pharmaceuticals, agrochemicals, and specialty polymers. It is particularly sought after by R&D chemists and process development teams in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), especially those requiring sterically hindered carboxylic acid derivatives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its chlorinated moiety introduces key functionality.
• Polymer Chemistry: Serves as a monomer or modifier in the synthesis of specialty polymers, including acrylic resins and coatings, to impart specific properties like weatherability or adhesion.
• Organic Synthesis Reagent: Employed in laboratories for esterification reactions, nucleophilic substitution, and as a precursor for generating other functionalized propanoate derivatives.
• Flavor & Fragrance Industry: Acts as an intermediate for creating complex ester-based aroma chemicals, contributing to unique scent profiles.
• Liquid Crystal & Electronic Materials: Investigated as a synthetic intermediate for materials used in display technologies and organic electronics.

Basic Information

Product Name	Ethyl 3-Chloro-2,2-Dimethylpropanoate
CAS No.	106315-37-1
Molecular Formula	C7H13ClO2
Molecular Weight	164.63 g/mol
Synonyms	Ethyl 3-Chloro-2,2-dimethylpropionate; 3-Chloro-2,2-dimethylpropionic Acid Ethyl Ester; 2,2-Dimethyl-3-chloropropionic Acid Ethyl Ester; NSC 332003; Propanoic acid, 3-chloro-2,2-dimethyl-, ethyl ester; Ethyl β-chloro-α,α-dimethylpropionate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Chloro-2,2-Dimethylpropanoate is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, and our quality control includes rigorous analytical testing such as GC/HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4280 - 1.4320
Density (20°C)	1.05 - 1.10 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.