Description

4-Bromo-2-Fluoro-1-Iodobenzene is a high-purity halogenated benzene derivative, a crucial building block in advanced organic synthesis. Its unique combination of bromine, fluorine, and iodine substituents makes it a versatile and valuable intermediate for creating complex molecular architectures. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the halogen atoms serve as handles for further functionalization.
• Liquid Crystal & OLED Materials: Serves as a building block for creating halogenated aromatic cores in advanced electronic and display materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalyst testing, and exploring new synthetic pathways.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and organometallic catalysts used in homogeneous catalysis.
• Fluorinated Compound Libraries: A valuable starting material for generating libraries of fluorinated compounds for screening in drug discovery programs.

Basic Information

Product Name	4-Bromo-2-Fluoro-1-Iodobenzene
CAS No.	105931-73-5
Molecular Formula	C6H3BrFI
Molecular Weight	300.89 g/mol
Synonyms	1-Bromo-4-fluoro-2-iodobenzene; 2-Fluoro-4-bromo-1-iodobenzene; 4-Bromo-2-fluoroidobenzene; Benzene, 4-bromo-2-fluoro-1-iodo-; 1-Iodo-4-bromo-2-fluorobenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-1-Iodobenzene is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with each shipment to guarantee consistency and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.