Description

5-Bromo-2-Chloroacetophenone is a versatile halogenated acetophenone derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and chlorine substituents, makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its halogenated structure.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form biaryl structures.
• Organic Synthesis Building Block: A versatile starting material for synthesizing heterocycles and complex aromatic compounds.

Basic Information

Product Name	5-Bromo-2-Chloroacetophenone
CAS No.	105884-19-3
Molecular Formula	C8H6BrClO
Molecular Weight	233.49 g/mol
Synonyms	1-(5-Bromo-2-chlorophenyl)ethanone; 2-Chloro-5-bromoacetophenone; 5-Bromo-2'-chloroacetophenone; α-Chloro-5-bromoacetophenone; 2-Chloro-5-bromo-1-phenylethanone; 1-Acetyl-5-bromo-2-chlorobenzene; 5-Bromo-2-chloro-1-phenylethanone; 5-Bromo-o-chloroacetophenone
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloroacetophenone is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting identity, purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.