Description

Imidacloprid Impurity 1 is a high-purity chemical reference standard used for analytical and research purposes. This compound is critical for ensuring the quality, safety, and regulatory compliance of the active pharmaceutical ingredient (API) Imidacloprid. It is primarily required by analytical laboratories, quality control departments, and research institutions involved in pesticide development and pharmaceutical impurity profiling. The material is essential for method validation, calibration, and the accurate quantification of impurities in commercial batches.

Application

• Pharmaceutical Reference Standard: Used as a certified impurity standard for the quality control and release testing of Imidacloprid API.
• Analytical Method Development: Serves as a critical component in developing and validating HPLC, GC, or LC-MS methods for impurity detection.
• Regulatory Compliance & Documentation: Essential for preparing regulatory submission dossiers (e.g., for FDA, EMA) that require full impurity characterization.
• Research & Development: Used in stability studies, degradation pathway elucidation, and metabolic research related to neonicotinoid compounds.
• Quality Assurance: Employed as an internal standard to monitor batch-to-batch consistency and ensure product purity specifications are met.
• Academic Studies: Utilized in university and institutional research focusing on environmental fate, toxicity, and analysis of pesticide residues.

Basic Information

Product Name	Imidacloprid Impurity 1
CAS No.	105828-41-9
Molecular Formula	C9H10ClN5O2
Molecular Weight	255.66 g/mol
Synonyms	1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-N-nitro-1H-imidazol-2-amine; Imidacloprid Impurity A; Imidacloprid Related Compound A; (E)-1-((6-Chloropyridin-3-yl)methyl)-N-nitroimidazolidin-2-imine; 2-Nitroimino-imidazolidine derivative of Imidacloprid; Nitroiminoimidazolidine impurity of Imidacloprid; Imidacloprid Nitroimino Impurity
EINECS	Contact for details

Quality Control

Every batch of Imidacloprid Impurity 1 (CAS 105828-41-9) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of pharmaceutical impurity standards. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, related substances, and identification tests performed using validated methods such as HPLC and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to Off-white Powder
Identification (IR)	Conforms to Reference Spectrum
Identification (HPLC)	Retention time corresponds to Reference Standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total Impurities ≤ 2.0% Any Individual Unknown Impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.