Description

Bruceine H is a bioactive quassinoid compound, a key constituent derived from the seeds of Brucea javanica. This high-purity reference standard is essential for pharmaceutical research, quality control, and the development of new therapeutic agents. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutraceutical, and botanical extract industries for its significant biological activity.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material for the identification, assay, and quality control of herbal medicines and finished products containing Brucea javanica extracts.
• Bioactivity Research: Used in pharmacological studies to investigate its anti-cancer, anti-inflammatory, anti-parasitic, and antiviral properties in vitro and in vivo.
• Natural Product Isolation & Analysis: A critical marker compound for the standardization and fingerprinting of Brucea javanica extracts in analytical laboratories.
• Preclinical Drug Development: Employed as a lead compound or intermediate in the research and development of new therapeutic formulations.
• Academic Research: Utilized in universities and research institutions for studies in phytochemistry, pharmacology, and molecular biology.
• Quality Assurance/Quality Control (QA/QC): Essential for ensuring batch-to-batch consistency, purity, and potency in the manufacturing of botanical dietary supplements.

Basic Information

Product Name	Bruceine H
CAS No.	105532-18-1
Molecular Formula	C₂₀H₂₈O₈
Molecular Weight	396.43 g/mol
Synonyms	Bruceine H; (1S,2R,5S,7S,10R,11S,14S,15R)-5,11-Dihydroxy-2,6,6,11,15-pentamethyl-14-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-16-oxatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-8-one; Yadanziolide H; Ailanthone analog
EINECS	Contact for details

Quality Control

Our Bruceine H is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods (NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.