Description

4-Bromo-2-Fluoro-1-(Trifluoromethoxy)Benzene is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the unique properties of the trifluoromethoxy and halogen substituents.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display technologies and organic light-emitting diodes (OLEDs).
• Functional Material Development: Employed in creating specialty polymers, coatings, and advanced materials that require specific electronic or steric properties.
• Cross-Coupling Reactions: The bromine substituent makes it a valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new fluorination methodologies and aromatic substitution patterns.

Basic Information

Item	Details
Product Name	4-Bromo-2-Fluoro-1-(Trifluoromethoxy)Benzene
CAS No.	105529-58-6
Molecular Formula	C7H3BrF4O
Molecular Weight	258.99 g/mol
Synonyms	1-Bromo-4-fluoro-2-(trifluoromethoxy)benzene; 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene; 2-Fluoro-4-bromo-α,α,α-trifluoroanisole; 2-Fluoro-4-bromophenyl trifluoromethyl ether; 4-Bromo-2-fluoro-α,α,α-trifluoroanisole; Benzene, 4-bromo-2-fluoro-1-(trifluoromethoxy)-; 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene (CAS 105529-58-6)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-1-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.