Description

2-Iodo-4-Methoxybenzaldehyde is a versatile aromatic aldehyde building block characterized by its iodine and methoxy substituents. This compound matters as a key intermediate in advanced organic synthesis, enabling the construction of complex molecules for pharmaceutical and material science research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its reactive aldehyde and halogen functional groups.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and metal complex formation.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and advanced polymers where its specific substitution pattern imparts desired electronic or steric properties.
• Chemical Biology & Proteomics: Acts as a derivatization agent or a building block for probes and tags used in studying biological systems and protein interactions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for scaling up novel synthetic pathways.

Basic Information

Product Name	2-Iodo-4-Methoxybenzaldehyde
CAS No.	105469-13-4
Molecular Formula	C8H7IO2
Molecular Weight	262.05 g/mol
Synonyms	4-Methoxy-2-iodobenzaldehyde; 2-Iodo-4-methoxybenzaldehyde; 2-Iodo-p-anisaldehyde; 4-Methoxy-2-iodobenzenecarboxaldehyde; 2-Iodo-4-methoxybenzenecarboxaldehyde; p-Anisaldehyde, 2-iodo-; 105469-13-4 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Iodo-4-Methoxybenzaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.